There is an urgent need to learn more about refractory epilepsy, where people continue to have seizures despite treatment with two or more epilepsy medications. Clinicians need to be able to identify people who are
The team expect to identify new information about the risk factors for developing refractory epilepsy. If the causes of refractory epilepsy are better understood, this could ultimately enable us to develop new strategies to prevent
Dr Adler’s Multi-centre Epilepsy Lesion Detection (MELD) project will create the largest collection of anonymised MRI data from patients with epilepsy caused by structural abnormalities from hospitals world-wide.
Genetic variations are a leading cause of epilepsy, particularly in those that encode proteins called ion channels. Ion channels regulate the passage of charged particles across the membranes of nerve cells and are responsible for
“FIRES” or febrile infection-related epilepsy syndrome is exactly what it sounds like – an explosive onset of the most difficult to treat relentless seizures (super-refractory status epilepticus, or SRSE).
Epilepsy is a complex condition with diverse symptoms and underlying mechanisms. Some of these mechanisms can be understood and their potential for new therapies is determined only by investigating the basic aspects of nerve cell
